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Thanks for the explanation! I saw several more downvotes at the time I made my comment, I think it was 4 downvotes for the parent comment and 2 for the second comment. Votes between instances aren’t always consistent, I’ve noticed when I switch accounts that the same comment’s votes can vary quite a lot.
Those will take a lot more time, but they’re possible. Sickle cell is the result of a single point mutation so is easier to tackle. MS and Ehlers-Danlos are the results of dozens of genetic mutations, so it would require really complex gene therapies.