I’m interested in building a power wall for home use. Typically you see lithium-ion batteries up to 14s for use in ebikes and all kinds of low-voltage DC applications. For home use you want 220V AC (or 110V AC for Americans).
An inverter would waste a lot of energy going from 12V to 220V at high wattages. The lower the voltage, the more amps are drawn and thus more energy becomes waste heat. You also need thick wires to not have them become fire hazards. The battery also gets strained when drawing high amps from them.
Would it be sensible to build a 60S battery? Transformation losses from 240VDC-> 220VAC should be quite minimal. You can put enough solar panels in series to make charging this battery sensible as well.
Of course there are obvious safety hazards with high voltages but there should be advantages as well, lower strain on battery cells and minimal DC->AC losses.
In addition to the other answers: You are mistaken regarding stress and losses on battery cell level, at least if you build the same overall batterry capacity at both voltage levels with the same cells.
Starting with the HV variant, the power is P = U * I. If you now build a LV variant, let’s say at U/4, with the same capacity, you will have 4 strains in parallel. So on pack level you will need 4 * I to get the same power, but inside the battery this current will split up into the 4 parallel strains. So each cell therefore again only has the current I.
Of course this is an ideal assumption. As you would have higher losses, e.g. in the wiring to the inverter, the overall power you need to draw from the battery increases. But it’s not as severe as it might seem based overall current increase on system level.
Edit: The formulas did some unintended formatting. 😅